|The purpose of this guide is to connect you with useful information and resources for embarking on a systematic review or other type of synthesis. Information about conducting standard literature reviews can be found here.|
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The terms synthesis and research review are often used interchangeably. The Canadian Institutes of Health Research defines synthesis as
“[T]he contextualization and integration of research findings of individual research studies within the larger body of knowledge on the topic.”
A synthesis must be reproducible and transparent in its methods and may synthesize qualitative or quantitative results.
When systematic reviews were the first type of synthesis to appear in the health care literature back in the 1970s, the main objective was to synthesize quantitative research studies. Limitations of traditional systematic reviews and meta-analyses led to the adaptation of syntheses to include:
While many syntheses begin with a clear question, their methodologies and the types of research evidence synthesized to answer the question can be quite different.
To help determine the most appropriate type of synthesis for your research question and purpose, you may find it helpful to consult the following articles.
Overview of 12 knowledge synthesis methods that go beyond the traditional systematic review (Kaster et al., 2016):
Fig. 1. Conceptual algorithm to optimize selection of a knowledge synthesis method for answering a research question.
Kastner, M., Antony, J., Soobiah, C., Straus, S. E., & Tricco, A. C. (2016). Conceptual recommendations for selecting the most appropriate knowledge synthesis method to answer research questions related to complex evidence. Journal of Clinical Epidemiology, 73, 43-49.
Mays, N., Roberts, E., & Popay, J. (2001). Synthesising research evidence. Studying the Organisation and Delivery of Health Services: Research Methods, 188-220.
Moher D., Stewart L. & Shekelle P. (2015). All in the family: systematic reviews, rapid reviews, scoping reviews, realist reviews, and more. Syst Rev, 4(1):1-2.