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Systematic Reviews & Other Syntheses

Introduction

Grey literature is the term used to describe literature that is not formally published as a book or journal article [1], including:

  • conference abstracts and papers,
  • preprints,
  • dissertations and theses,
  • governmental or private sector research,
  • ongoing or unpublished clinical trial data,
  • statistical publications,
  • internal reports or working papers,
  • technical reports.

Related library guides:

In addition to the information provided about grey literature on this page, there are related library guides on:

Grey Literature Resources

Some library databases contain grey literature in addition to journal articles. For example, Web of Science Core Collection and Embase contain conference content, while PsycINFO and CINAHL contain some dissertations. Since health-related library databases do not generally provide comprehensive coverage of grey literature, other resources should be searched to identify literature that is not formally published as well.
 

Dissertations and Theses Databases

Preprint Servers and Databases

Clinical Trial Registries

For quantitative systematic reviews of healthcare interventions, it is strongly recommended to search clinical trial registries (particularly ClinicalTrials.gov and WHO ICTRP) for on-going and unpublished trials in order to limit publication bias. 

Note: Since August 2019, eligible reports of RCTs or quasi-RCTs from ClinicalTrials.gov and WHO ICTRP are being identified and systematically added to Cochrane CENTRAL. However, other study designs in these trial registries (e.g. cohort studies) are not identified and added to Cochrane CENTRAL.

Other Grey Literature Sources

Bibliography

  1. Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.

Related Articles:

Training Module

An inter-professional team led by Queen's has set out to develop an open access module series titled The Essentials of Conducting Systematic Reviews to introduce researchers to all stages of the systematic review process.

Check out Module 3: Searching for Eligible Studies.